WebPERK, a member of the GCN2 subfamily of Ser/Thr protein kinases, phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of … WebApr 27, 2010 · Interventional strategies currently under development to block disease caused by Shiga toxins may be categorized as: (i) toxin receptor analogues; (ii) toxin intracellular transport inhibitors; (iii) anti-toxin antibodies; and (iv) probiotic bacteria.
PDI (C81H6) Rabbit mAb Cell Signaling Technology
WebPhospho-Erk5 (Thr218/Tyr220) Antibody detects immunoprecipitated or transfected levels of Erk5 phosphorylated at threonine 218 and tyrosine 220. This antibody cross-reacts with phosphorylated Erk1 and Erk2. It does not cross-react with phosphorylated p38 MAPK or SAPK/JNK. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification WebOct 13, 2024 · In this study, we found that PERK was significantly activated during RANKL-induced osteoclast differentiation; knockdown of PERK by siRNA and inhibition of PERK by GSK2606414, respectively,... 18歲公民權公投案
Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody
WebSep 9, 2011 · PERK counteracts the pro-survival properties of Akt in ER-stressed cells (A) Isogenic WT MEFs and Akt DKO MEFs were treated with 1 μM thapsigargin (TG) for the … WebMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human ATF-6 alpha protein. Background Activating Transcription Factor - 6 (ATF-6) is a transmembrane glycoprotein of the endoplasmic reticulum (ER). WebSep 27, 2011 · Assays in transiently transfected COS-1 cells demonstrated the phosphorylation of Myc-tagged wild-type PERK but not of a Myc-tagged Thr 799 →Ala … 18歲公民權結果