Phorbol myristoyl acetate
WebPhorbol myristate acetate (PMA; phorbol ester) activates protein kinase C, which then activates a wide range of signaling pathways, including ERK via effects on the upstream … WebCD3, CD28, phorbol myristoyl acetate (PMA), ionomycin, phytohemagglutinin, interleukin (IL)-2, or IL-4 [4]. On 3, NK cells, 4-1BB is upregulated following ligation of the FcRγIII Fc receptor (CD16) by the Fc portion of mAb. In addition to activated immune effectors, 4-1BB is also expressed on innate immune cell populations, including
Phorbol myristoyl acetate
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WebPhorbol myristoyl acetate (PMA) and phosphatase inhibitor cocktail were from Sigma-Aldrich (St. Louis, MO, USA). The following Western blot antibodies were used: anti-PDHE1 and anti-VDAC (Invitrogen, Carlsbad, CA, USA); anti-PKC by measuring the increase in absorbance at 340 nm of a reactionand anti-Tim23 (BD Biosciences, San Jose, CA, WebMay 3, 2013 · Overview Product name Phorbol 12-myristate 13-acetate (PMA), PKC activator Description PKC activator Alternative names PMA CAS Number 16561-29-8 Chemical structure Properties Associated products Applications Images Protocols Datasheets and documents References (31) Customer reviews and Q&As
WebMar 31, 2016 · Some of the canonic immunostimulatory agents known to induce 4-1BB upregulation on T cells include: Con A, plate-bound anti-CD3, CD28, phorbol myristoyl acetate (PMA), ionomycin, phytohemagglutinin, interleukin (IL)-2, or IL-4 [3, 4]. On NK cells, 4-1BB is upregulated following ligation of the FcRγIII Fc receptor (CD16) by the Fc portion of … Webdisulfonic acid, phorbol myristoyl acetate (PMA), desferrioxamine, and all other reagents were from Sigma. 55FeCl 3 (9.1 mM, 20 mCi/mg) was from PerkinElmer Life Sciences. A 55Fe-NTA solution was prepared by incubating 55FeCl 3 (9.1 mM) and NTA (45.5 mM) for 1 h. The resulting 55Fe-NTA solution was mixed at a 1:9 molar ratio with unlabeled
WebProduct Name Phorbol 12-myristate 13-acetate Cat No. : BP685, BP685-1, BP685-10, BP685-5 CAS No 16561-29-8 Synonyms PMA Recommended Use Laboratory chemicals. Uses … WebIn order to test the biological relevance and potential interaction of MLK 3 with protein kinase C-mediated signaling pathways, human MLK 3 was stably expressed in rat glomerular mesangial cells using a retroviral vector (LXSN) and the effects of phorbol myristoyl acetate (PMA) on DNA synthesis and osteopontin mRNA expression were examined.
WebPhorbol 12-myristate 13-acetate (PMA), PKC activator (DMSO solution) Description PKC activator (DMSO solution) Alternative names PMA Biological description Potent nanomolar activator of protein kinase C in vivo and in vitro. Binds to C1 domain of protein kinase C, induces membrane translocation and enzyme activation.
WebA phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA. Entry Term(s) 12-Myristoyl-13 … irs 457b limits for 2023WebJun 30, 1988 · It is concluded that phorbol esters stereospecifically enhance the Ca 2+ -sensitivity of glutamate release, but that higher concentrations may be required than for protein kinase C translocation in the same preparation. Instead the enhancement may be related to the rapid inactivation of protein kinase C which occurs with phorbol esters. … irs 4686 formWebPhorbol-12-myristate-13-acetate, CAS 16561-29-8, acts as an extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro at nM concentrations. … irs 45w creditWebPhorbol 12-myristate 13-acetate C36H56O8 CID 27924 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ... irs 457 contribution limitsWebGeneral description. Phorbol 12-myristate 13-acetate is a phorbol ester. It works as a tumor promoter and is involved in gene transcription, cell growth, differentiation, programmed … portable handheld printer on youtubeportable handheld oscillating spindle sanderWebZoom. Phorbol-12-myristate-13-acetate, CAS 16561-29-8, acts as an extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro at nM concentrations. MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS. irs 4582 form